Mitochondrial Complex I deficiency has been reported in several diseases and strongly linked to patients with Parkinson ’s disease. However, there is poor mechanistic understanding of the pathways involved and no treatment ...
Tbx20, a T-box transcription factor, is known to be crucial for cardio genesis and murine models with Tbx20 knockout fail to survive beyond E10.5. Tbx20 mutations correspond with severe congenital heart defects including ...