Taxus wallichiana Zucc. (synonym Taxus baccata subsp. wallichiana (Zucc.) Pilg.) or Himalayan yew, has drawn a lot of interest globally. This is mostly attributed to its remarkable abundance of paclitaxel, an exceptionally ...
Sirtuins have attained recognition in the sphere of epigenetic regulation, owing to its affiliation with numerous biological processes including metabolism and genomic stability. Many post translational modifications (PTMs) ...
The HIV-1 accessory proteins (Vpr, Vif, Vpu, and Nef) are multifunctional proteins that play a critical role in the virus progression and contributing to AIDS pathogenesis. These proteins engage with numerous host cellular ...
Considering the present plastic pollution crisis, this thesis work reported the phytotoxicity of polystyrene micro/nanoplastics (M/NPs) in onion with effects on seed germination, root growth, and cytotogenotoxicity. The ...
The etiological link of arsenic with bladder cancer (BC) is well established across the globe. The molecular pathogenesis of arsenic induced BC should be explored to identify potential markers of clinical importance for ...
Fluoride is necessary for tooth and bone development, but excessive exposure causes different system disorders including male reprotoxic consequences. The purpose of this study was to investigate the extent of fluoride ...
Bamboos, a category of non-timber grasses, belong to the family Poaceae and the subfamily Bambusoideae. Therefore, phylogenetically they are close to rice (Oryza sativa), Brachypodium and other reference grasses. It has ...
Over the past decade a great attention has been paid to decipher the consequences of impending climate change scenario on the physiological and biochemical functioning of aquatic organisms. Anthropogenic activities primarily ...
Background: The physical activity of schoolbag carriage is a form of mandatory load carriage with a myriad of physiological consequences, the most common being pain occurrence and changes in physiological responses. The ...
In mammals, interleukin-6 (IL-6) and interleukin-10 (IL-10) has an important function during the reproductive processes, however, the functions of IL-6 and IL-10 in fish have not been elucidated. In the present study, there ...
Tbx20, a T-box transcription factor, is known to be crucial for cardio genesis and murine models with Tbx20 knockout fail to survive beyond E10.5. Tbx20 mutations correspond with severe congenital heart defects including ...
Under acidic soil and aluminum stress conditions, the crop plants are facing several growth defects. Particularly significant decrease in root growth, nutrient uptake and low yield are the very common problems. Besides, ...
Bamboos belong to the monocotyledonous plant family Poaceae and subfamily Bambusoideae. Bamboos represent an extreme example of perennialism, where the reproductive phase begins after completion of an extended vegetative ...
Background of the research: Medicinal plants, their identification, preservation and phytochemical profiling have become extremely important due to excessive demand of plant derived bioactive secondary metabolites as natural ...
Triple Negative Breast Cancer (TNBC) being devoid of the hormonal receptors manifests a difficult challenge for different therapeutic approaches. As TRAIL (TNF Related Apoptosis Inducing Ligand) is known for its ability ...
Apoptosis is a regulated cell death characterized by cell shrinkage, nuclear condensation, DNA fragmentation, membrane blebbing. There are several apoptosis regulators eg: BCL2, Bcl-xL, BAX, Survivin, FLIP, XIAP, cIAP etc. ...
Conventional treatment strategies involving antibiotics are gaining accelerated challenges as a result of increasing antibiotic resistance by pathogenic microorganisms. A significant quantity of therapeutic research had ...
Sirtuins are a class of proteins biologically acting as epigenetic modulators. They are generally found to be involved in regulating the essential cellular processes like metabolism, aging and genome stability. In our ...
Arsenic toxicity is a major worldwide health problem and has been associated with several reproductive system disorders. The study was designed to investigate the protective role of casein–pea-enriched protein diet /formulated ...
Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C plays an important role during B-cell transformation and subsequent development of several B-cell lymphomas specifically in those who are from immuno-compromised background. ...