Epstein-Barr virus (EBV) nuclear oncoprotein EBNA3C plays an important role during B-cell transformation and subsequent development of several B-cell lymphomas specifically in those who are from immuno-compromised background. ...
In rapidly proliferating cancer cells, endoplasmic reticulum (ER) tends to be overloaded with unfolded and misfolded proteins due to high metabolic demand. With the limited protein folding capacity of ER, cancer cells ...